Real Madrid will face Cultural Leonesa and Barcelona will take on Hercules in the last 32 of the Copa del Rey.
The European champions, who were ejected from last season s competition after fielding the ineligible Denis Cheryshev, will take on the Segunda B side who became a viral sensation in 2014 when they wore a kit designed to appear like a tuxedo in a pre-season charity match.
Holders Barcelona will take on Hercules, who overcame Cornella this week, while Atletico Madrid will meet Guijuelo and last season s beaten finalists Sevilla have been drawn against fourth-tier Formentera.
The first legs will be played on November 30, with the return matches scheduled for December 21.
Copa del Rey draw in full:
Toledo v Villarreal
Formentera v Sevilla
Cultural Leonesa v Real Madrid
Hercules v Barcelona
Guijuelo v Atletico de Madrid
Racing de Santander v Athletic Bilbao
UCAM Murcia v Celta Vigo
Cordoba v Malaga
Valladolid v Real Sociedad
Huesca v Las Palmas
Nastic v Alaves
Alcorcon v Espanyol
Sporting Gijon v Eibar
Granada v Osasuna
Leganes v Valencia
Betis v Deportivo La Coruna